Elucidation of Genetic and Electrophysiological Basis of
Hereditary Lethal Arrhythmias
1.
Research Project:
Mutations in cardiac ion channel genes are responsible in part for a spectrum of hereditary lethal arrhythmias including congenital long QT syndrome and Brugada syndrome. These syndromes predispose affected individuals to sudden death. Therefore, defining their pathophysiology and establishing effective strategies for the prophylaxis of sudden death are urgent issues in public health. This project is aimed at elucidating the molecular basis of sudden death in hereditary lethal arrhythmias and ultimately developing new prophylactic approaches that potentially replace the implantable devices. The project goals will be achieved by close collaboration among clinical and research institutes around the world, as well as by exploiting cutting-edge technology such as iPS (induced pluripotent stem) cells.
There is one chair position in the Graduate School of Biomedical Sciences. Nagasaki University will publicly seek a motivated young researcher who is capable of promoting projects under his/her charge in the following research fields:
(1)
Genetic screening and electrophysiological analysis of hereditary lethal arrhythmias
(2)
Electrophysiological analysis of human iPS cell-derived cardiomyocytes that originate from patients with hereditary lethal arrhythmias
(3)
Computer simulation to delineate the basis mechanisms of hereditary lethal arrhythmias
(4)
Establishment of genetically-engineered animals relevant to hereditary lethal arrhythmias and functional analysis in vivo
3.
Qualifications:
(1)
Applicants must have a Ph.D.
(2)
Applicants must have significant research achievements and motivation in the research filed to which he/she will be assigned.
(3)
Applicants must have high-level ability to perform collaborative studies with overseas research/clinical institutions and to carry out creative research on his/her own.
(4)
Applicants must not work for any other institutes or companies during the project.
(5)
Applicants under 40 years of age at the time of employment are preferred.
4.
Research Period :
From as early as May 1, 2010 to March 31, 2014
(In the case of an applicant who lives abroad, he/she may not be able to start on May 1 due to lengthy reviews and various other procedures.)
A successful applicant will be employed as a full-time assistant professor during the above period.
If the performance is deemed excellent at the end of the determined research period, he/she will be promoted to associate professor.
5.
Salary and Research Fund:
Salary: Approximately JPY 7,000,000 per year
(Standard Nagasaki University employment rules and regulations will be applied.)
Research fund: Approximately JPY 6,000,000 per year for the first two years
6.
Research Facilities and Equipments:
Facilities and equipments will be preferentially prepared within the major research project.
7.
Required Documentation:
The following documents must be submitted with one original and one copy.
Each should be provided either in English or in Japanese.
(1)
Resume/CV with a passport-size photo attached
(2)
Complete list of all published papers
(3)
Copies of your five major papers
(4)
Abstract of your research up to the present date (one to two A4 pages)
(5)
Research project title and what you expect to accomplish--hopes, goals, resolution, etc. (one to two A4 pages)
(6)
Names and contact information of two people who can be approached in reference to your work.
*(1) can be downloaded in MS-Word format below, but other documents require no special format. Download application forms （MS-Word 68KB)
8.
Deadline for the Application:
Application forms must reach Nagasaki University by Friday, 17:00, February 26, 2010.
Applications missing the deadline will not be accepted.
9.
Miscellaneous:
(1)
Submitted materials will NOT be returned to the applicant as a rule.
(2)
After passing the documents examination, applicants are expected to come to Nagasaki University to attend a seminar in which the applicants will give a lecture, and undertake an oral examination on their current research. The University will cover airfare and transportation fees. In the case of overseas applicants, the visiting schedule may be arranged with the University.
Research Planning Division
Research Promotion and International Affairs Department
Nagasaki University
1-14 Bunkyo-machi
Nagasaki 852-8521
Japan
* Please make sure to use registered mail such as EMS, DHL, FedEx, etc. and specify "Tenure Track Assistant Professor Application (Elucidation of Genetic and Electrophysiological Basis of Hereditary Lethal Arrhythmias )" on the envelope in red ink.
